1 ml of the drug contains:
imidocarb dipropionate – 120 mg
The liquid is light yellow, transparent, sterile.
Imidocarb dipropinate – a derivative of icarbanilide, provides a wide range of antiprotozoal action against pathogens of piroplasmidosis in mono- or mixed invasions – babesia Babesia bovis, B. bigemina, B. solchica (Francaiella colchica), B. divergens, B. ovis, B. motasi caballi, B. equi (Nuttallia equi), B. canis, B. gibsonii, B. vogeli, teileria Theileria annulata, T. sergenti, T. mutans, T. orientalis, T. ovis, T. recondita, T. hirci , T. tarandirangiferis, rickettsiae of the genus Anoplasma Anaplasma marginale, A. centrale, A. ovis, A. phagocytophilum and the genus Ehrlichia Ehrlichia canis, E. chaffeensis.
The mechanism of antiprotozoal action is based on inhibition of the process of aerobic glucose metabolism and DNA synthesis in piroplasmids, which causes their death.
After parenteral administration, the drug is rapidly absorbed and reaches its maximum concentration in the blood in 1-2 hours, the therapeutic concentration is maintained for 4-6 weeks.
Metabolized to a small extent, accumulates mainly in the kidneys and liver, excreted mainly in the feces, in small quantities in the urine.
Imidocarb dipropinate according to the degree of impact on the body belongs to moderately dangerous substances (hazard class 3 according to GOST 12.1.007-76).
Method of application and dosage
Before use, the vial with the drug is thoroughly shaken and used:
- Cattle, buffaloes, zebu, camels: subcutaneously, once, the dose per 100 kg of body weight is: babesiosis – 2 ml, anaplasmosis, mixed invasions – 2.5 ml, prevention – 2 ml;
- sheep, goats, mouflons, deer: babesiosis, anaplasmosis – 0.2 ml per 10 kg of body weight, intramuscularly or subcutaneously, once;
- horses, mules, donkeys: intramuscularly, the dose per 100 kg of body weight is: Babesia caballi – 2 ml, course – 2 injections in 24 hours, Babesia equi – 3 ml, course – 4 injections in 3 days;
- dogs: babesiosis – 0.3-0.5 ml per 10 kg of body weight (subcutaneously, once), if necessary, repeat after 14 days at a dose of 0.2 ml.
When group animals are kept and blood parasitic diseases are detected, the drug is administered to the entire herd in a prophylactic dose, the injection is repeated in cattle after 6 weeks, and in animals of other species in 4 weeks. The protective effect of the drug lasts 14-21 days after administration.